| 1944 | Foundation of Arcana |
| 1964 | Relocation to Spittal |
| 1984 | Takeover of Arcana by Merck |
| 1987 - 1990 | New facilities for pharmaceutical production and safety warehouse |
| 1989 | Merger of Arcana and Austro Merck to Merck GesmbH |
| 1992 | Beginning of contract manufacturing activities |
| 1997 | Separation from Merck Vienna, foundation of Merck Spittal as company of the Merck Group |
| 2002 | Modernisation of the machinery |
| 2004 | Implementation of the three layer tablets technology |
| 2005 - 2006 | Expansion of the pharmaceutical production, global production site of Merck Serono |
| 2007 - 2008 | Construction of high-bay warehouse |
| 2009 | Expansion of the three layer tablet production |